Peer-reviewed articles
2010
Zebrafish models to study drug abuse-related phenotypes. Stewart, A, Wong, K, Cachat J, Gaikwad S, Kyzar E, Wu N, Hart P, Piet V, Utterback E, Elegante M, Tien D, Kalueff A. Revs Neurosci, 2010; in press. Measuring behavioral and endocrine responses to novelty stress in adult zebrafish. Cachat J, Stewart A, Grossman L, Gaikwad S, Kadri F, Min Chung K, Wu N, Wong K, Roy S, Suciu C, Goodspeed J, Elegante M, Bartels B, Elkhayat S, Tien D, Tan J, Denmark A, Gilder T, Kyzar E, DiLeo J, Frank K, Chang K, Utterback E, Hart P, Kalueff, A. Nature Protocols, 2010; in press. Homebase behavior of zebrafish in novelty-based paradigms. Stewart A, Cachat J, Wong K, Gaikwad S, Gilder T, Dileo J, Chang K, Utterback E, Kalueff A. Behav Processes, 2010; 85: 198-203. - PDF Modeling seizure-related behavioral and endocrine phenotypes in adult zebrafish. Wong K, Stewart A, Gilder T, Wu N, Frank K, Gaikwad S, Suciu C, DiLeo J, Utterback E, Chang K, Grossman L, Cachat J, Kalueff A. Brain Research, 2010; 1348: 209-15. - PDF Characterization of behavioral and endocrine effects of LSD on zebrafish. Grossman L, Utterback E, Stewart A, Gaikwad S, Wong K, Elegante M, Tan J, Gilder T, Wu N, DiLeo J, Cachat J, Kalueff A. Behavioral Brain Research, 2010; 214: 277-84. - PDF Neurosteroid vitamin D system as a non-traditional drug target in neuropsychopharmacology. Stewart A, Wong K, Cachat J, Elegante M, Gilder T, Mohnot S, Wu N, Minasyan A, Tuohimaa P, Kalueff A. Behavioral Pharmacology, 2010; 21: 420-6. PDF The developing utility of zebrafish in modeling neurobehavioral disorders. Stewart A, Kadri F, DiLeo J, Chung K, Cachat J, Goodspeed J, Suciu C, Roy S, Gaikwad S, Wong K, Elegante M, Elkhayat S, Wu N, Gilder T, Tien D, Grossman L, Tan J, Denmark A, Bartels B, Frank K, Beeson E, Kalueff A. Int J. Compar Psychol, 2010; 23: 104-121. - PDF Domain interplay in mice and men: new possibilities for the "Natural Kinds" theory of emotion. JE Warnick, JL LaPorte, AV Kalueff, New Ideas Psychol 2010, in press. - PDF The effects of chronic social defeat stress on mouse self-grooming behavior and its patterning. Denmark A, Tien D, Wong K, Chung A, Cachat J, Goodspeed J, Grimes C, Elegante M, Suciu C, Elkhayat S, Bartels B, Jackson A, Rosenberg M, Chung K, Badani H, Kadri F, Tan J, Roy S, Gaikwad S, Stewart A, Zapolsky I, Gilder T, Kalueff A. Behav Brain Res 2010, 2010; 208: 553-9. - PDF Analyzing habituation responses to novelty in zebrafish (Danio rerio). Wong K, Elegante M, Bartels B, Elkhayat S, Tien D, Roy S, Goodspeed J, Suciu C, Tan J, Grimes C, Chung A, Rosenberg M, Gaikwad S, Duncan A, Jackson A, Kadri F, Chung K, Stewart A, Gilder T, Beeson E, Zapolsky I, Wu N, Cachat J, Kalueff A. Behav Brain Res 2010; 208: 450-457. - PDF Modeling withdrawal syndrome in zebrafish. Cachat J, Canavello P, Elegante M, Bartels B, Hart P, Bergner C, Egan R, Duncan A, Tien D, Chung A, Wong K, Goodspeed J, Grimes C, Elkhayat S, Suciu C, Rosenberg M, Chung K, Kadri F, Roy S, Gaikwad S, Stewart A, Zapolsky I, Gilder T, Mohnot S, Beeson E, Tan J, Amri H, Zukowska A, Glasgow E, Soignier R, Kalueff A. Behav Brain Res 2010; 208: 371-6. - PDF Qui non proficit, deficit: Experimental models for ‘integrative’ research of affective disorders. LaPorte JL, Egan RE, Hart PC, Bergner CL, Cachat JM, Canavello PR, Kalueff AV. J Affect Disorders 2010; 121: 1-9. - PDF Conserved role for the serotonin transporter gene  in rat and mouse neurobehavioral endophenotypes. Kalueff AV, Oliver J, Nonkes L, Homberg J. Neurosci Biobehav Reviews 2010 34: 373-386. - PDF
2009
25-Hydroxyvitamin D3 is an agonistic vitamin D receptor ligand. Lou Y, Molnar F, Perakyla M, Qiao S, Kalueff A, St-Arnaud R, Carlberg C, Tuohimaa P. J Steroid Biochem Mol Biol 2009, in press. - PDF Vitamin D, nervous system and aging. Tuohimaa P, Keisala T, Cachat J, Kalueff A. Psychoneuroendocrinology 2009; 34S: S278-S286. - PDF Understanding behavioral and physiological phenotypes of stress and anxiety in zebrafish. Egan R, Bergner C, Hart R, Cachat J, Canavello P, Elegante M, Elkhayat S, Bartels B, Tien A, Tien D, Mohnot S, Beeson E, Glasgow E, Amri H, Zukowska Z, Kalueff A. Behavl Brain Res 2009; 205: 38-44. - PDF Premature aging in Vitamin D Receptor mutant mice. Keisala T, Minasyan A, Lou YR, Zou J, Zhang Y, Kalueff AV, Pyykko I, Tuohimaa P. Steroid Biochem Mol Biol. 2009, 115: 91-97. - PDF Vestibular dysfunction in vitamin D receptor mutant mice. Minasyan A, Keisala T, Zou J, Zhang Y, Toppila E, Syvala H, Lou YR, Kalueff AV, Pyykko I, Tuohimaa P. J Steroid Biochem Mol Biol. 2009; 114:161-166. - PDF Serum cholesterol and expression of ApoAI, LXRβ and SREBP2 in vitamin D receptor knock-out mice. Wang JH, Keisala T, Solakivi T, Minasyan A, Kalueff AV, Tuohimaa P. J Steroid Biochem Mol Biol. 2009; 113: 222-226. - PDF
2008
Refining psychiatric genetics: from 'mouse psychiatry' to understanding complex human disorders. Laporte JL, Ren-Patterson RF, Murphy DL, Kalueff AV. Behav Pharmacol. 2008;19(5-6):377-84. - PDF Hybridizing behavioral models: a possible solution to some problems in neurophenotyping research? Kalueff AV, LaPorte JL, Murphy DL, Sufka K. Prog Neuropsychopharmacol Biol Psychiatry. 2008;32(5):1172-8. - PDF Domain interplay concept in animal models of neuropsychiatric disorders: a new strategy for high-throughput neurophenotyping research. Kalueff AV, Ren-Patterson RF, LaPorte JL, Murphy DL. Behav Brain Res. 2008;188(2):243-9. - PDF Perspectives on genetic animal models of serotonin toxicity. Kalueff AV, LaPorte JL, Murphy DL. Neurochem Int. 2008 Mar-Apr;52(4-5):649-58. - PDF Anxiety and otovestibular disorders: linking behavioral phenotypes in men and mice. Kalueff AV, Ishikawa K, Griffith AJ. Behav Brain Res. 2008;186(1):1-11. - PDF Understanding Stress-Related Behavioral Phenotypes: Report from the 1st International Neuroscience Summer School and the 11th International “Stress and Behavior” Conference. Kalueff AV. Neuronal Plasticity. 2008 - PDF Progressive hearing loss in mice with a mutated vitamin D receptor gene. Zou J, Minasyan A, Keisala T, Zhang Y, Wang JH, Lou YR, Kalueff A, Pyykkö I, Tuohimaa P. Audiol Neurootol. 2008;13(4):219-30. - PDF The regular and light-dark Suok tests of anxiety and sensorimotor integration: utility for behavioral characterization in laboratory rodents. Kalueff AV, Keisala T, Minasyan A, Kumar SR, LaPorte JL, Murphy DL, Tuohimaa P. Nat Protoc. 2008;3(1):129-36. - PDF
2007
Pharmacological modulation of anxiety-related behaviors in the murine Suok test. Kalueff AV, Keisala T, Minasyan A, Tuohimaa P. Brain Res Bull. 2007; 14;74(1-3):45-50. - PDF Locomotory patterns, spatiotemporal organization of exploration and spatial memory in serotonin transporter knockout mice. Kalueff AV, Jensen CL, Murphy DL. Brain Res. 2007;1169:87-97 - PDF Hypolocomotion, anxiety and serotonin syndrome-like behavior contribute to the complex phenotype of serotonin transporter knockout mice. Kalueff AV, Fox MA, Gallagher PS, Murphy DL. Genes Brain Behav. 2007;6(4):389-400. - PDF Brain-derived neurotrophic factor, serotonin transporter, and depression: comment on Kaufman et al. Kalueff AV, Wheaton M, Ren-Patterson R, Murphy DL. Biol Psychiatry. 2007;61(9):1112-3 - PDF Neophobia, sensory and cognitive functions, and hedonic responses in vitamin D receptor mutant mice. Minasyan A, Keisala T, Lou YR, Kalueff AV, Tuohimaa P. J Steroid Biochem Mol Biol. 2007;104(3-5):274-80. - PDF Aberrant nest building and prolactin secretion in vitamin D receptor mutant mice. Keisala T, Minasyan A, Järvelin U, Wang J, Hämäläinen T, Kalueff AV, Tuohimaa P. J Steroid Biochem Mol Biol. 2007;104(3-5):269-73. - PDF What's wrong with my mouse model? Advances and strategies in animal modeling of anxiety and depression. Kalueff AV, Wheaton M, Murphy DL. Behav Brain Res. 2007;179(1):1-18. - PDF The developing use of heterozygous mutant mouse models in brain monoamine transporter research. Kalueff AV, Ren-Patterson RF, Murphy DL. Trends Pharmacol Sci. 2007;28(3):122-7. - PDF Influence of paternal genotypes on F1 behaviors: lessons from several mouse strains. Kalueff AV, Keisala T, Minasyan A, Tuohimaa P. Behav Brain Res. 2007;177(1):45-50. - PDF Behavioral neuroscience, exploration, and K.C. Montgomery's legacy. Kalueff AV, Zimbardo PG. Brain Res Rev. 2007;53(2):328-31.- PDF Neurosteroid hormone vitamin D and its utility in clinical nutrition. Kalueff AV, Tuohimaa P. Curr Opin Clin Nutr Metab Care. 2007;10(1):12-9 - PDF Role of GABA in anxiety and depression. Kalueff AV, Nutt DJ. Depress Anxiety. 2007;24(7):495-517. - PDF Analyzing grooming microstructure in neurobehavioral experiments. Kalueff AV, Aldridge JW, LaPorte JL, Murphy DL, Tuohimaa P. Nat Protoc. 2007;2(10):2538-44. - PDF The importance of cognitive phenotypes in experimental modeling of animal anxiety and depression. Kalueff AV, Murphy DL. Neural Plast. 2007;52087. - PDF Neurobiology of memory and anxiety: from genes to behavior. Kalueff AV. Neural Plast. 2007;78171. - PDF 10th Jubilee Multidisciplinary International Conference of Neuroscience and Biological Psychiatry “Stress and Behavior”. Kalueff AV. Neural Plasticity. 2007 - PDF Mapping convulsants' binding to the GABA-A receptor chloride ionophore: a proposed model for channel binding sites. Kalueff AV. Neurochem Int. 2007;50(1):61-8. - PDF
2006
Are serotonin transporter knockout mice 'depressed'?: hypoactivity but no anhedonia. Kalueff AV, Gallagher PS, Murphy DL. Neuroreport. 2006;17(12):1347-51. - PDF BDNF in anxiety and depression. Kalueff AV, Avgustinovich DF, Kudryavtseva NN, Murphy DL. Science. 2006;312(5780):1598-9. - PDF The vitamin D neuroendocrine system as a target for novel neurotropic drugs. Kalueff AV, Minasyan A, Keisala T, Kuuslahti M, Miettinen S, Tuohimaa P. CNS Neurol Disord Drug Targets. 2006;5(3):363-71. - PDF Thalamic calcification in vitamin D receptor knockout mice. Kalueff A, Loseva E, Haapasalo H, Rantala I, Keranen J, Lou YR, Minasyan A, Keisala T, Miettinen S, Kuuslahti M, Tuchimaa P. Neuroreport. 2006;17(7):717-21.- PDF Behavioural anomalies in mice evoked by "Tokyo" disruption of the Vitamin D receptor gene. Kalueff AV, Keisala T, Minasyan A, Kuuslahti M, Miettinen S, Tuohimaa P. Neurosci Res. 2006;54(4):254-60. - PDF Temporal stability of novelty exploration in mice exposed to different open field tests. Kalueff AV, Keisala T, Minasyan A, Kuuslahti M, Tuohimaa P. Behav Processes. 2006;72(1):104-12. - PDF Increased severity of chemically induced seizures in mice with partially deleted Vitamin D receptor gene. Kalueff AV, Minasyan A, Keisala T, Kuuslahti M, Miettinen S, Tuohimaa P. Neurosci Lett. 2006;394(1):69-73. - PDF Hair barbering in mice: implications for neurobehavioural research. Kalueff AV, Minasyan A, Keisala T, Shah ZH, Tuohimaa P. Behav Processes. 2006;71(1):8-15. - PDF
2005
Behavioural characterization in rats using the elevated alley Suok test. Kalueff AV, Minasyan A, Tuohimaa P. Behav Brain Res. 2005;165(1):52-7. - PDF The role of hair in swimming of laboratory mice: implications for behavioural studies in animals with abnormal hair. Kalueff AV, Tuohimaa P. Lab Anim. 2005;39(4):370-6. - PDF Anticonvulsant effects of 1,25-dihydroxyvitamin D in chemically induced seizures in mice. Kalueff AV, Minasyan A, Tuohimaa P. Brain Res Bull. 2005;67(1-2):156-60. - PDF Contrasting grooming phenotypes in three mouse strains markedly different in anxiety and activity (129S1, BALB/c and NMRI). Kalueff AV, Tuohimaa P. Behav Brain Res. 2005;160(1):1-10. - PDF The grooming analysis algorithm discriminates between different levels of anxiety in rats: potential utility for neurobehavioural stress research. Kalueff AV, Tuohimaa P. J Neurosci Methods. 2005;143(2):169-77. - PDF The Suok ("ropewalking") murine test of anxiety. Kalueff AV, Tuohimaa P. Brain Res Brain Res Protoc. 2005;14(2):87-99. - PDF Calcidiol and prostate cancer. Tuohimaa P, Golovko O, Kalueff A, Nazarova N, Qiao S, Syvälä H, Talonpoika R, Lou YR. J Steroid Biochem Mol Biol. 2005;93(2-5):183-90. - PDF Mouse grooming microstructure is a reliable anxiety marker bidirectionally sensitive to GABAergic drugs. Kalueff AV, Tuohimaa P. Eur J Pharmacol. 2005;508(1-3):147-53. - PDF Abnormal behavioral organization of grooming in mice lacking the vitamin D receptor gene. Kalueff AV, Lou YR, Laaksi I, Tuohimaa P. J Neurogenet. 2005;19(1):1-24. - PDF
2004
Contrasting grooming phenotypes in C57Bl/6 and 129S1/SvImJ mice. Kalueff AV, Tuohimaa P. Brain Res. 2004;1028(1):75-82. - PDF Increased grooming behavior in mice lacking vitamin D receptors. Kalueff AV, Lou YR, Laaksi I, Tuohimaa P. Physiol Behav. 2004;82(2-3):405-9. - PDF Grooming analysis algorithm for neurobehavioural stress research. Kalueff AV, Tuohimaa P. Brain Res Brain Res Protoc. 2004;13(3):151-8. - PDF Impaired motor performance in mice lacking neurosteroid vitamin D receptors. Kalueff AV, Lou YR, Laaksi I, Tuohimaa P. Brain Res Bull. 2004;64(1):25-9. - PDF Intranasal administration of human IL-6 increases the severity of chemically induced seizures in rats. Kalueff AV, Lehtimaki KA, Ylinen A, Honkaniemi J, Peltola J. Neurosci Lett. 2004;365(2):106-10. - PDF Increased anxiety in mice lacking vitamin D receptor gene. Kalueff AV, Lou YR, Laaksi I, Tuohimaa P. Neuroreport. 2004;15(8):1271-4. - PDF Experimental modeling of anxiety and depression. Kalueff AV, Tuohimaa P. Acta Neurobiol Exp (Wars). 2004;64(4):439-48. - PDF Mechanisms of neuroprotective action of vitamin D(3). Kalueff, A. V., K. O. Eremin, et al. Biochemistry (Mosc). 2004;69(7): 738-41. - PDF
2001
Persistent c-fos expression and NADPH-d reactivity in the medulla and the lumbar spinal cord in rat with short-term peripheral anosmia. Kalueff AV, Maisky VA, Pilyavskii AI, Makarchuk NE. Neurosci Lett. 2001;301(2):131-4. - PDF
1996
Role of GABA in memory and anxiety. Kalueff A, Nutt DJ. Depress Anxiety. 1996-1997;4(3):100-10. - PDF